2-Propenamide,N-[2-(3,4-dimethoxyphenyl)ethyl]-3-phenyl-, (2E)- CAS: 29946-61-0
Product Name: Sichuan Pepper Extract
English Name: WGX-50
Also Known As: GX-50; Lemairamin; N-(3,4-Dimethoxyphenethyl)cinnamamide; N-[2-(3,4-dimethoxyphenyl)ethyl]-3-phenylacrylamide
CAS No.: 29946-61-0
Molecular Formula: C19H21NO3
Molecular Weight: 311.37
Purity: 98.0%
Appearance: White powder
Packaging: 1 kg/bag, 25 kg/drum
Storage Conditions: Store in a sealed, dry, room temperature environment away from direct sunlight.
Note: All products of our company are for export only, intended for laboratory and research use in legal and non-patented regions. Personal or animal use is strictly prohibited. Those who misuse it illegally bear full responsibility for any consequences.
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Product Description
Basic Information: Product Name: CAS NO: 29946-61-0 Chinese Alias: Molecular Formula: C19H21NO3 Molecular Weight: 311.381 English Name: (2E)-N-[2-(3,4-dimethoxyphenyl)ethyl]-3-phenyl-2-propenamide EINECS: Density: English Alias: (E)-N-[2-(3,4-dimethoxyphenyl)ethyl]-3-phenyl-2-propenamide; (E)-Cinnamamide,N-(3,4-dimethoxyphenethyl)-; Lemairamin Flash Point: Melting Point: Boiling Point:
Hua Jiao Su, also known as WGX-50, is a natural compound extracted from chili peppers. Studies have found that it can inhibit Aβ-induced neuronal apoptosis and reduce the accumulation of Aβ oligomers in the cerebral cortex. Additionally, WGX-50 has been proven to improve cognitive abilities in mice. Research suggests that WGX-50 may prevent protein-protein assembly between amyloid-beta molecules. WGX-50 has also been found to have significant effects on the skin, such as reducing wrinkles and improving skin elasticity. Apart from the natural compounds derived from the Sichuan pepper plant, there are now more synthetic compounds available for various applications, which are better suited for the market.
Features:
(1) High purity: Hua Jiao Su can achieve high-purity products through refined production processes. High purity means better bioavailability.
(2) Safety: It is highly safe with minimal adverse reactions.
(3) Stability: Hua Jiao Su has good stability and maintains its activity and efficacy under different environmental and storage conditions.
Applications: Hua Jiao Su is an amide compound extracted from the bark of the Sichuan pepper plant. Currently used as a dietary supplement, it also acts as an agonist of the α7 nicotinic acetylcholine receptor (α7nAChR) and is fully synthetic. In preclinical studies, WGX-50 has shown promising results, including inhibiting Aβ-induced neuronal cell apoptosis, lowering neuronal calcium toxicity, and reducing the accumulation of Aβ oligomers in the cerebral cortex.

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