Product Description

5-Amino-1-methylquinoline chloride is an enzyme that is overexpressed during skeletal muscle aging, associated with repairing NAD+ pathway damage, dysregulated sirtuin1 activity, and increased muscle stem cell senescence. It promotes myoblast differentiation in vitro and enhances the fusion and regeneration of muscle stem cells in aged mice. Additionally, it is a potent inhibitor of nicotinamide N-methyltransferase (NNMT), selectively binding to residues at the NNMT substrate-binding site. NNMT, a newly discovered cytosolic enzyme, regulates the levels of nicotinamide precursors necessary for NAD+ biosynthesis, playing a crucial role in modulating the NAD+ salvage pathway. 5-Amino-1-methylquinoline chloride also acts on your microbiome to reduce fat tissue. When excess fat cells accumulate, your body overproduces an enzyme called NNMT (nicotinamide N-methyltransferase). The more NNMT present, the more fat your body stores. By inhibiting NNMT, 5-amino-1-methylquinoline chloride helps your body shed extra weight. Key features include high purity, achieved through refined production processes, ensuring better bioavailability; target specificity, effectively inhibiting NNMT activity and impacting nicotinamide metabolism; stability, maintaining its activity and efficacy under various environmental and storage conditions; and promising development prospects due to its multiple characteristics, attracting extensive research and application interest. Applications of 5-amino-1-methylquinoline chloride include promoting myoblast differentiation and serving as a supplement to reduce fat and improve liver fat.

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