HBT1 CAS: 489408-02-8
Product Name: HBT1
English Name: HBT1
English Alias: YDL223C
CAS No.: 489408-02-8
Molecular Formula: C16H17F3N4O2S
Molecular Weight: 386.40
Purity: 99.0%
Appearance: White powder
Packaging: 1kg/bag; 25kg/drum
Storage Conditions: Store in a sealed, dry, room temperature environment away from direct sunlight.
Note: All products of our company are for export only, intended for laboratory and research use in legal and non-patented regions. Personal or animal use is strictly prohibited. Those who misuse it illegally are fully responsible for any consequences that arise.
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Product Description
Product Introduction: BT1 binds to the ligand-binding domain of the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPA-R) in a glutamate-dependent manner. This means that when glutamate is present, HBT1 is a molecule that can only bind to specific sites on the AMPA-R protein, and this binding helps regulate the protein's activity. AMPA receptors are expressed throughout the central nervous system and play crucial roles in neuronal communication, sensory processing, learning, memory, and synaptic plasticity. They are major contributors to excitatory neurotransmission, mediating rapid, fast-desensitizing excitation at many synapses and participating in early responses to glutamate at synaptic regions. AMPA receptors are often co-expressed with NMDA receptors at synapses, together promoting synaptic plasticity processes involved in learning, memory, excitotoxicity, and neuroprotection. Brain-derived neurotrophic factor (BDNF) is a neurotrophic factor that plays an important role in the maintenance and expansion of neurons, exerting powerful and diverse effects on the proliferation, differentiation, survival, and death of both neuronal and non-neuronal cells. It acts as a neuromodulator that aids in neuronal plasticity during learning and memory. Therefore, it is essential for health and well-being.
Features:
1. High Purity: HBT1 can be obtained through refined production processes to achieve high purity, which translates to better bioavailability.
2. Safety: HBT1 has been proven to be safe.
3. Stability: HBT1 exhibits good stability, maintaining its activity and efficacy under various environmental and storage conditions.
Applications: HBT1 is a novel low-efficacy AMPA receptor enhancer that induces the production of brain-derived neurotrophic factor (BDNF) and has minimal excitatory effects on primary neurons. It binds to the ligand-binding domain of AMPA-R in a glutamate-dependent manner. Together, they promote synaptic plasticity processes involved in learning, memory, excitability, and neuroprotection. It can enhance cognitive abilities in the brain. It is typically added to daily

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